Aids virus , New forms of Aids contraction Automatic Aids true Male to make intercourse. Stage 1 (HIV infection): The CD4+ cell count is at least 500 cells per microliter. Stage 2 (HIV infection): The CD4+ cell count is 350 to 499. Stage 3 (advanced HIV disease or AHD): The CD4+ cell count is 200 to 349. Stage 4 (Acquired immunodeficiency syndrome [AIDS]): The CD4+ cell count is less than 200 What are the 5 stages of AIDS? Stages of HIV infection Seroconversion illness. Some people experience a short illness soon after they contract HIV. ... The asymptomatic stage of HIV. Once seroconversion is over, most people feel fine and don't experience any symptoms. ... Symptomatic HIV. ... Late-stage HIV. Automatic Aids : Form of Aids contracted by male to male sex . If a male ejaculate and let off semen into another man both men contract Aids Automatically thats the significance names of the name of type or stage called "Automatic Aids" (swindle street name Auto) not to be confused with Autoamun disease. Automatic is the most contagious form of Aids with 15 touches of hand to hand contact you can contract "Automatic Aids" so for Women or men who aren't homosexual but a wife or family living with a openly or closet homosexual contract this highly contagious disease just by sitting in the same chair with shorts or riding in a cab and your skin touches the seat wearing shorts , you can contract "Automatic Aids" . After the deadly full-blown Aids contracted mostly thrue Std (Sexually transmitted disease) is Automatic Aids . Hiv is the symptoms of catching aids .With proper treatment all aids you can heal from and it's not undeveloped in hospital. All hospital's that treat Hiv , full blown aids or Automatic Aids have successfull treatment for all forms of Aids . First Thiers Inpatient that consist of live in facility with 24 hour lock door proceedure and most hospitals treatment is no longer than a weeks and you come home recovered . Outpatient mean you can go home everyday but have to report to Aids treatment everyday for 3-6 weeks minimum for full recovery from aids if you don't report local police can escort you to treatment if unwilling by force for your safety and health but more importantly the people around you who can contract this disease easily not alerted by the infectious . Dr. SEBI son website has the organic colinipin which guarantees to get rid of all disease and infections etc. . With Rejuvenation of all organs coming from this pill you can order the colinipin online and deliver to your house in days . Testimony of SEBI Colinipin Rapper Lil Kim : Who suffered from a rare melon skin disease which Michael Jackson is the only other case where his entire body was covered having this rare skin Melon disease . The colinipin taken 2 years ago rejuvenated her organs sending her skin tone to her original color just rejuvenated back to the purist texture which can be inhanced by multi day Vitamin . Just Taken Dr.Sebi organic colinipin surgery a pill and 1 hour bed rest also made for children . Page 1 of 7 Page 2 of 7List of Different forms of Aids Desmond Tutu 21 301 2020 info@hiv-research.org.za Facebook page opens in new window Twitter page opens in new window Instagram page opens in new window Desmond Tutu Health Foundation 5 Strategies to Cure HIV You are here: Whilst a person living with HIV can suppress the virus with antiretrovirals, there is no cure. A cure for HIV would be the total eradication of the virus from the body. However, this is not the only option that scientists are looking into. Here are some of the strategies scientists are looking into for an HIV cure. Light Painting | JonathanCohen via Photopin Shock and kill technique HIV hides in reservoir cells in the body and can remain silent as long as a patient takes antiretroviral therapy. As soon as a patient stops taking ARTs, the reservoir virus wakes up and starts replicating all around the body again. Shock and Kill would ‘wake up’ these reservoirs to activate the silent virus. Whilst counter- intuitive, the idea is to wake up every single virus and kill all the activated cells, destroying the reservoir in one go. If one virus survives then there is always a risk that it will be able to duplicate and the virus will return. Currently, scientists have identified drugs that will ‘shock’ or ‘wake up’ the silent reservoir cells. The next challenge is to identify a drug or method that can subsequently destroy these infected cells and avoid healthy cells. When destroying cells in the body, there is always a risk that drugs will target healthy cells, so this research moves carefully to avoid unnecessary damage. References Pharmacological reactivation of virus as a cure strategy – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031321/ Locks and Lockers | Eyad Elbayoumi via Photopin Lock and Block Technique The ‘Lock and Block’ technique takes the opposite approach to ‘Shock and Kill’. This method aims to trap HIV in its reservoir cell so that it can never be reactivated. Whilst the virus is still Page 2 of 7 Page 3 of 7present in the body, it is trapped away so that it cannot escape its host cell and cannot replicated. This technique is being looked into as an alternative to ‘Shock and Kill’. Scientists are currently testing drugs’ abilities to effectively trap HIV in a host cell without disrupting the genetic material of uninfected cells. Ideally, a drug would lock HIV away then deplete the reservoir so there was no possibility of the virus returning. Current issues that are being researched are drugs not locking away HIV tightly enough. References http://programme.ias2017.org/PAGMaterial/eposters/5814.pdf ...new strategy (‘block and lock’), designed to silence the HIV reservoir, rather than eradicate it. The goal of this strategy would be to increase treatment intervals and maybe even obtain a state of ‘HIV remission’. https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-015-0517-y Due to the non-inducible property of the ‘deep’ viral reservoir, the ‘permanent silencing’ approach could be considered as a suitable cure strategy. Unlike ‘shock and kill’ strategies, this approach focuses on silencing or locking the HIV-1 proviruses in cells. Radiate | sax via Photopin Stem Cell Transplants Only one man has ever been ‘cured’ of HIV. Timothy Ray Brown, otherwise known as the ‘Berlin patient’, was cured of HIV after receiving a stem cell transplant for another condition. Due to a rare genetic mutation in the donated stem cells, Brown’s immune system could fight off the HIV in his body. Over a decade later, he is still HIV-free and actively campaigning for HIV research and speaking about his experience. A stem cell transplant involves destroying the body’s immune system, then introducing new stem cells that rebuild. This is commonly used to treat leukemia, a cancer of the blood and bone marrow that attacks the body. Brown had a stem cell donation from a specific donor who had a rare gene mutation. Most people have the gene called CCR5 in their DNA. This produces a receptor on human cells that HIV can ‘latch onto’ and thus infiltrate the cell barrier. However, this donor had the mutation called CCR5 – delta32 which produces a receptor that HIV is unable to interact with. The virus can no longer invade human cells and the human host is resistant to HIV. When Brown received the stem cells with this CCR5 – delta32 mutation, his body DNA adapted and he became resistant to HIV. However, the details behind why Brown was cured of HIV are complex and difficult to repeat. Even repeating the procedure in other patients, their HIV has come back after a period in remission. There are still elements that scientists don’t understand enough to reproduce the results in other HIV-positive patients. Additionally, stem cell transplants are dangerous, expensive and require very specific donors otherwise the body can reject the new cells. Stem cell transplantation probably won’t become a mainstream avenue for an HIV cure. Personal Photography Cropped | Iron-Photographer Amarand Agasi via PhotoPin AntiRetroviral Therapy as a Cure Page 3 of 7 Page 4 of 7It has been shown that treating the virus within the first 48 hours of exposure can significantly reduce the size of the HIV reservoir hidden in the body. This method is suitable for certain people (e.g. new born babies of HIV-positive mothers), but will not work for everyone. In infants born to HIV-positive mothers, those who started ARTs within 6 to 12 months of birth had reduced mortality rates and a smaller HIV reservoir. However, many people do not get access to HIV treatment early enough and many people do not realise they have HIV until months after they are first exposed. This is another reason why it is important to go for an HIV test regularly so that you always know your status and can act quickly if you do become infected. Overall, researchers feel that ARTs alone will not make a cure strategy. Instead, ARTs might make up part of a cure package. References https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031321/ ...it is apparent that early ART is instrumental in minimizing the pool of latently infected cells and most likely will be exploited further as a means to a functional cure https://www.ncbi.nlm.nih.gov/pubmed/19020325 Early HIV diagnosis and early antiretroviral therapy reduced early infant mortality by 76% and HIV progression by 75%. . http://betablog.org/early-antiretroviral-therapy-progress-in-hiv-cure-research/ The complexity of HIV infection—which establishes difficult-to-eliminate viral reservoirs very early—means that prompt ART alone may not be sufficient as an HIV cure strategy. Red Light | Travis Goodspeed via Flickr A Vaccine Whilst technically prevention and not a cure, a vaccination would be a powerful tool in beating HIV. Many HIV vaccines have been trialed and only one has had significant results. It is called the RV144 trial which started in 2003, in Thailand. A cohort received a trial vaccine and were tested for HIV three years later. From the volunteers, the rate of HIV was 31% lower in the cohort who received the vaccine compared to those who received the placebo. This study gave scientists hope that there could be a possibility for a vaccine. However, the strain of HIV found in Thailand is different to the strain found in sub-Saharan Africa, so the vaccine prototype needs to be adjusted the strains of the virus that are most common in South Africa. There are projects to create a vaccination however, it is complicated to create a lasting vaccination. Researchers at the Desmond Tutu HIV Foundation, an HIV vaccine trial, HVTN 702. This trial, which began in 2016, is predicted to run for five years. HIV-negative, South African adults receive a series of injections at five different time points that rally the body’s defenses against HIV. If successful, this could be the biggest step towards a vaccine and we are closer than we have ever been. Some trial work has been done to create infusions that give participants protection, but the protection only lasts for a month or so before another dose is needed. Many diseases in the past have been close-to-eradicated, if not fully eradicated, thanks to vaccinations: polio, mumps, smallpox, tetanus and measles to name a few. References http://www.nejm.org/doi/pdf/10.1056/NEJMoa0908492 Page 4 of 7 Page 5 of 7In the intention-to-treat analysis involving 16,402 subjects, there was a trend toward the prevention of HIV-1 infection among the vaccine recipients, with a vaccine efficacy of 26.4% ... In the perprotocol analysis involving 12,542 subjects, the vaccine efficacy was 26.2% ... In the modified intention-to-treat analysis involving 16,395 subjects (with the exclusion of 7 subjects who were found to have had HIV-1 infection at baseline), the vaccine efficacy was 31.2% https://www.unicef.org/pon96/hevaccin.htm In all, vaccines have brought seven major human diseases under some degree of control – smallpox, diphtheria, tetanus, yellow fever, whooping cough, polio, and measles. Still Searching for a Cure Research is still ongoing to find a way to beat HIV. Until there is a cure, HIV-infected people should access ARTs as soon as possible and stick to their daily dose. Written by Caroline Reid Alternative Treatments for HIV and AIDS Medically reviewed by Daniel Murrell, M.D. — Written by The Healthline Editorial Team — Updated on April 24, 2020 Treating symptoms Supplement safety Takeaway Alternative treatments for HIV Many people with HIV or AIDS use complementary and alternative medicine (CAM) in combination with traditional medical treatments to improve their health and well-being. There is some evidence that CAM treatments can relieve some symptoms of HIV infection or AIDS. However, there is no evidence that these treatments can treat or cure these conditions. And there’s also little information regarding the side effects of these treatments. And just because a treatment is natural does not mean it’s safe. Some of these treatments can interact with certain medications. People with HIV or AIDS should tell their healthcare provider if they’re interested in using CAM to help manage their symptoms. Read on to learn about which options may be safe and which ones to avoid. Alternative therapy for HIV symptoms There is relatively little research on the use of CAM treatments for relieving symptoms of HIV or AIDS. However, some common CAM treatments have been shown to improve the symptoms of other illnesses. In some cases, these treatments might be worth a try for someone with HIV infection or AIDS. Body therapies Yoga and massage therapy may help reduce pain for some people. ResearchTrusted Source has shown that yoga can also improve feelings of overall health and reduce anxiety and depression. It has even been shown to improve levels of CD4 cells, which are immune cells that are attacked by HIV. Page 5 of 7 Page 6 of 7Acupuncture may help with nausea and other treatment side effects. Acupuncture is an ancient Chinese medical practice that involves placing thin, solid needles into various pressure points on the body. This can release chemicals in the body that can help relieve pain. Relaxation therapies Meditation and other forms of relaxation treatment can help reduce anxiety. They may improve the ability to cope with the stress of a chronic illness such as HIV. Herbal medicine Herbal medications should be used with caution. There isn’t enough evidence to support the use of these drugs for relieving HIV symptoms. However, a brief course of certain herbs may support immunity in people with HIV. Research has shown that milk thistle is one example. Milk thistle is a common herb used in people to improve liver function and does not interact significantly with antivirals. Keep in mind though that other herbs may interact with conventional HIV treatments. People with HIV should tell their healthcare provider before using any herbal treatments. This allows their provider to monitor for any drug interactions or side effects. Medical marijuana Loss of appetite is common in people with HIV. And some antiviral medications can upset the stomach and make it harder to keep up with scheduled medication doses. Marijuana can help reduce pain, control nausea, and increase appetite. However, medical marijuana is legal only in certain states. In addition, smoking marijuana is associated with many of the same health risks as the smoking of any substance. A healthcare provider can provide more information. There’s little evidence to suggest that medical marijuana will interact with modern HIV management medications. Still, people with HIV should consult their healthcare provider before using marijuana to treat their symptoms. The provider will monitor for possible drug interactions or respiratory complications. Interactions between supplements and HIV treatment Supplements should be used with caution by people living with HIV or AIDS. Some supplements may be safe to use, while others could cause problems. People with HIV or AIDS should talk to their healthcare provider about what vitamins and minerals they should take to improve their health. Supplements to avoid Certain supplements are known to cause problems with the effectiveness of HIV treatment. Four of these are garlic, St. John’s wort, echinacea, and ginseng. Garlic supplements can make certain HIV treatments much less effective. If garlic is taken with certain medications, it could result in too much or too little of the drug in the blood. This problem outweighs any possible benefits of these supplements on the immune system. That said, eating fresh garlic is not known to cause problems. St. John’s wort is a popular supplement used to treat depression. However, it can make HIV treatment less effective. People with HIV should not use this supplement. Page 6 of 7 Page 7 of 7Echinacea and ginseng are purported to boost immune function. However, both can interact with certain HIV medications. It may be okay to use these supplements depending on the HIV therapy. A healthcare provider should be consulted. Supplements that may be helpful Supplements that may be useful in people with HIV include: calcium and vitamin D to improve bone health fish oil to reduce cholesterol selenium to slow the progression of HIV vitamin B-12 to improve the health of pregnant women and their pregnancies whey or soy protein to help with weight gain The takeaway HIV and AIDS can cause various symptoms, and some alternative treatments could help provide relief. But when considering alternative treatment options, people with these conditions should always talk to their healthcare provider first. A healthcare provider can help prevent any potential drug interactions and perhaps suggest other options that could help reduce symptoms. For people living with HIV or AIDS, working with a healthcare provider is the best way to explore options to help improve their health and well-being. Page 7 of 7
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